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- MEDICINE, Page 61Laid Low by the Flu
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- Americans are suffering the worst epidemic in five years
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- It comes in winter and is harder to dodge than a speeding
- snowball. This year the debilitating and sometimes deadly
- scourge of influenza is unusually virulent. So many people have
- taken to their bed with chills, aching muscles and fever that
- doctors are overwhelmed, offices are decimated, and some
- schools have temporarily shut their doors. Nearly 8,100
- Americans, most of them elderly, are known to have died of flu
- and flu-related illnesses, and the figure is rising daily. The
- Centers for Disease Control has officially declared it an
- epidemic, the worst outbreak of flu in the U.S. in at least
- five years.
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- The first widespread cases of flu appeared in Montana, New
- Mexico and Utah in mid-December, slightly earlier than normal.
- Within weeks, the disease broke out in Texas, Mississippi and
- Georgia and then along the Eastern Seaboard. Says Dr. Margaret
- Tipple, an epidemiologist at the CDC: "At this point, it's
- virtually coast to coast."
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- In fact, it spans most of the northern hemisphere. From
- Britain to the Soviet Union, the flu has hit millions of
- Europeans, including Pope John Paul, Queen Elizabeth and
- Princess Diana. Britain was hit so badly that staff shortages
- and patient overloads forced hospitals to put off surgery that
- could wait. Several trials at London's Old Bailey had to be
- delayed.
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- The flu is hard to contain because it is highly contagious,
- comes in many varieties, and can originate almost anywhere. It
- has plagued humanity at least since 412 B.C., according to an
- account by the Greek physician Hippocrates. By far the most
- devastating flu season on record was in 1918-19, when some 20
- million people worldwide -- including 500,000 in the U.S. --
- died of the "Spanish flu."
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- Scientists first isolated a flu virus, named type A, in 1933
- and subsequently found two other variants, now known as types
- B and C. Individual strains are named for the place where they
- are first identified. Most of this season's flu has been
- triggered by a nasty strain of influenza A, called A-Shanghai.
- A few cases of A-Taiwan and B-Yamagata (Japan) have also turned
- up.
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- The classic symptoms of flu, which begin to appear about 48
- hours after exposure to the virus, include a sudden fever,
- chills, sore throat, headache, muscle pains, lethargy and a
- persistent dry cough. Although most of the symptoms subside
- after two to three days, victims remain contagious for an
- additional three or four days.
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- The virus spreads easily, traveling in droplets spewed into
- the air by sneezing and coughing or through contact with mucus
- on hands or objects. Transmission is faster in places with poor
- ventilation, such as rooms with closed windows, crowded
- classrooms, nursing homes and public transportation systems.
- On planes, where the air is continuously recirculated, just one
- flu-ridden passenger can infect all the rest.
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- For most patients, a bout of flu means a few missed days of
- work or school. But for people 65 and over and for those who
- have chronic heart or respiratory problems, diabetes, asthma
- or weakened immune systems, the disease can easily be fatal.
- Less able to fend off infections, these individuals are more
- susceptible to bronchitis, pneumonia and, occasionally, kidney
- failure and heart attacks. In an average year, flu is a factor
- in about 20,000 deaths in the U.S. The majority of A-Shanghai
- victims have been elderly, and all 50 states have discovered
- outbreaks in nursing homes and other long-term-care facilities.
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- Flu shots are the best protection. Though a vaccine does not
- necessarily prevent the disease, it can lessen the severity.
- But designing the right vaccine is difficult because the
- viruses mutate, changing their chemical profile from year to
- year. Today's A-Shanghai may soon be supplanted by one that is
- substantially different. What is more, entirely new types of
- flu viruses appear every few years. Months before each flu
- season, scientists must guess which strains will be most active
- and then tailor a vaccine to combat them. Sometimes their
- forecast is wrong, and the vaccine is virtually useless. In
- 1976, for example, the anticipated swine-flu epidemic never
- materialized.
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- This year the vaccine seems to work, but not enough people
- have received it. Ordinarily, the CDC recommends the shots for
- senior citizens, nursing-home residents, people with AIDS,
- anyone who is susceptible to lung and heart ailments, and for
- health workers and others who deal with flu patients. This
- A-Shanghai strain is so virulent, however, that anyone who
- wants to avoid it should probably be inoculated.
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- By Andrea Dorfman. Reported by Don Winbush/Atlanta.
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- ____________________________________________________________ NOW
- THAT YOU'VE GOT IT
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- Once the flu bug bites, there is no quick cure. A doctor
- will recommend bed rest and plenty of liquids. It is important
- to stay home, especially since co-workers and schoolmates can
- easily catch the disease. For high-risk patients, physicians
- may prescribe amantadine, an antiviral drug that reduces fever
- and respiratory problems caused by strains of influenza A.
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